Finding a solution to this problem is one of the greatest challenges faced by scientists today.
You know me - I like a challenge.
It's going to be a difficult job but I'm sure she'll rise to the challenge.
I went with two friends from school, we had a big adventure there and we had to face many challenges. (Preliminary English Test; B1; Portuguese)
a challenge to the authority of the President
The one occasion in which Jack seems childish is when his challenge to Ralph's leadership fails and he weeps with humil[i]ation. (Certificate of Proficiency in English; C2; Portuguese)
Children challenge their parents' authority far more nowadays than they did in the past.
His daughter had just challenged him and he was struggling for a decision. (First Certificate in English; B2; German)